Recombinant Mouse Noxo1 Protein, Myc/DDK-tagged

• Cat.No.: Noxo1-4468M
• Product Overview: Purified recombinant protein of mouse full-length NADPH oxidase organizer 1 (Noxo1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity.
• Molecular Mass: 38.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Noxo1 NADPH oxidase organizer 1 [ Mus musculus (house mouse) ]
• Official Symbol: Noxo1
• Synonyms: NOXO1; NADPH oxidase organizer 1; nox organizer 1; sorting nexin-28; hslt; Snx28; P41NOX; P41NOXA; P41NOXB; P41NOXC; 2310034C04Rik
• Gene ID: 71893
• mRNA Refseq: NM_027988
• Protein Refseq: NP_082264
• UniProt ID: Q8VCM2