Recombinant Mouse Nle1 Protein, Myc/DDK-tagged

• Cat.No.: Nle1-4429M
• Product Overview: Purified recombinant protein of mouse full-length notchless homolog 1 (Nle1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in regulating Notch activity (Probable). Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival.
• Molecular Mass: 53.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nle1 notchless homolog 1 [ Mus musculus (house mouse) ]
• Official Symbol: Nle1
• Synonyms: Nle1; notchless homolog 1; N; Nle; notc; l11Ju; l11Jus1; l11Jus4; AL022765; BC018399; notchless protein homolog 1; Notchless gene homolog; novel WD40 repeat containing protein
• Gene ID: 217011
• mRNA Refseq: NM_145431
• Protein Refseq: NP_663406
• UniProt ID: Q8VEJ4