Recombinant Human NLE1 Protein (2-485 aa), His-SUMO-tagged
| Cat.No. : | NLE1-1152H |
| Product Overview : | Recombinant Human NLE1 Protein (2-485 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Biochemicals. Protein Description: Full Length of Mature Protein. |
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| Description : | Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several mbers of the Wnt pathway, probably via its effects on Notch activity. Required during bryogenesis for inner mass cell survival. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His&SUMO |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 69.2 kDa |
| Protein length : | 2-485 aa |
| AA Sequence : | AAAVPDEAVARDVQRLLVQFQDEGGQLLGSPFDVPVDITPDRLQLVCNALLAQEDPLPLAFFVHDAEIVSSLGKTLESQAVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
| Gene Name | NLE1 notchless homolog 1 (Drosophila) [ Homo sapiens ] |
| Official Symbol | NLE1 |
| Synonyms | Nle; |
| Gene ID | 54475 |
| mRNA Refseq | NM_018096.3 |
| Protein Refseq | NP_060566.2 |
| UniProt ID | Q9NVX2 |
Not For Human Consumption!
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