Recombinant Mouse Nfkbib Protein, Myc/DDK-tagged

• Cat.No.: Nfkbib-4399M
• Product Overview: Purified recombinant protein of mouse full-length nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta (Nfkbib), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes an inhibitor of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB). The encoded protein prevents NF-kappaB-mediated transcription activation by sequestering it in the cytosol. In response to signals that induce NF-kappaB, such as cytokines and growth factors, the encoded protein undergoes phosphorylation, triggering its rapid ubiquitination and proteasomal degradation. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 37.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta [ Mus musculus (house mouse) ]
• Official Symbol: Nfkbib
• Synonyms: NFKBIB; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; NF-kappa-B inhibitor beta; ikB-B; NF-kappa-BIB; I-kappa-B-beta; I(Kappa)B(beta); nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; IkB; IkBb; IKB-beta; IKappaBbeta; MGC36057
• Gene ID: 18036
• mRNA Refseq: NM_010908
• Protein Refseq: NP_035038
• UniProt ID: Q60778