Recombinant Mouse Mmp19 Protein, Myc/DDK-tagged

• Cat.No.: Mmp19-4099M
• Product Overview: Purified recombinant protein of mouse full-length matrix metallopeptidase 19 (Mmp19), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein develop a diet-induced obesity due to adipocyte hypertophy, exhibit decreased susceptibility to chemical carcinogen-induced skin tumors and early onset of tumoral angiogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 59.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Mmp19 matrix metallopeptidase 19 [ Mus musculus (house mouse) ]
• Official Symbol: Mmp19
• Synonyms: MMP19; matrix metallopeptidase 19; matrix metalloproteinase-19; MMP-19; matrix metalloproteinase 19; matrix metalloproteinase RASI; MGC123370
• Gene ID: 58223
• mRNA Refseq: NM_021412
• Protein Refseq: NP_067387
• UniProt ID: Q9JHI0