Recombinant Mouse Mib1 Protein, Myc/DDK-tagged

Cat.No. : Mib1-4064M
Product Overview : Purified recombinant protein of mouse full-length mindbomb E3 ubiquitin protein ligase 1 (Mib1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
  • Download
Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
Molecular Mass : 110.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Mib1 mindbomb E3 ubiquitin protein ligase 1 [ Mus musculus (house mouse) ]
Official Symbol Mib1
Synonyms MIB1; mindbomb homolog 1 (Drosophila); E3 ubiquitin-protein ligase MIB1; mind bomb-1; skeletrophin; mind bomb homolog 1; DAPK-interacting protein 1; DAPK-interacting protein-1; Mib; DIP-1; mKIAA1323; E430019M12Rik; MGC18948
Gene ID 225164
mRNA Refseq NM_144860
Protein Refseq NP_659109
UniProt ID Q80SY4

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All Mib1 Products

Required fields are marked with *

My Review for All Mib1 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon