Recombinant Mouse Mgp protein, His & S-tagged

• Cat.No.: Mgp-7011M
• Product Overview: Recombinant Mouse Mgp aa. (Tyr20~Tyr104 (Accession # P19788)) fused with N-terminal His & S tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His&S
• Protein Length: Tyr20~Tyr104
• Description: This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. This protein also inhibits angiogenesis. Mice lacking a functional copy of this gene exhibit impaired differentiation of endothelial cells, reduced stature, and calcification and rupture of the vasculature leading to premature death.
• Form: Freeze-dried powder
• Molecular Mass: 20kDa as determined by SDS-PAGE reducing conditions.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.5.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in ddH2O.

Gene Information

• Gene Name: Mgp matrix Gla protein [ Mus musculus (house mouse) ]
• Official Symbol: Mgp
• Synonyms: Mgp; matrix Gla protein; Mglap; matrix gamma-carboxyglutamate (gla) protein
• Gene ID: 17313
• mRNA Refseq: NM_008597.4
• Protein Refseq: NP_032623.1
• UniProt ID: P19788