Recombinant Mouse matrix metallopeptidase 9 Protein, Tag Free

• Cat.No.: MMP9-040M
• Product Overview: The sequence (Accession # NP_038627) corresponding to the catalytic domain (aa 112-445) of Mouse MMP-9 was expressed in E. coli. The recombinant mouse MMP-9 was purified from bacterial lysate and refolded using proprietary technique.

Specification

• Species: Mouse
• Source: E.coli
• Tag: Non
• Protein Length: 112-445aa
• Description: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis.
• Tag: Non
• Form: Solution
• Molecular Mass: 40 kDa
• Purity: ≥95% by SDS-PAGE
• Applications: Protease activity
• Usage: Research use
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 300 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl2, 20 μM ZnCl2, pH=7.5
• References: 1. J. F. Woessner et al., J.Biol.Chem. 263 (1988), 16918-16925
  2. J. F. Woessner, Jr., FASEB J. 5 (1991), 2145-2154
  3. S. M. Wilhelm et al., J.Biol.Chem. 264 (1989), 17213-17221

Gene Information

• Gene Name: Mmp9 matrix metallopeptidase 9 [ Mus musculus ]
• Official Symbol: Mmp9
• Synonyms: MMP9; matrix metallopeptidase 9; matrix metalloproteinase-9; GELB; Gel B; gelatinase B; 92kD gelatinase; 92kDa gelatinase; 92 kDa gelatinase; collagenase type IVB; 92kD type IV collagenase; 92kDa type IV collagenase; 92 kDa type IV collagenase; matrix metalloproteinase 9; Clg4b; MMP-9; B/MMP9; AW743869; pro-MMP-9
• Gene ID: 17395
• mRNA Refseq: NM_013599
• Protein Refseq: NP_038627
• UniProt ID: P41245