Recombinant Mouse Lzts2 Protein, Myc/DDK-tagged

• Cat.No.: Lzts2-3887M
• Product Overview: Purified recombinant protein of mouse full-length leucine zipper, putative tumor suppressor 2 (Lzts2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
• Molecular Mass: 72.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lzts2 leucine zipper, putative tumor suppressor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Lzts2
• Synonyms: Lzts2; leucine zipper, putative tumor suppressor 2; LAPSER1; BC014695; mKIAA1813; leucine zipper putative tumor suppressor 2; protein LAPSER1; putative tumor suppressor LAPSER1
• Gene ID: 226154
• mRNA Refseq: NM_001130526
• Protein Refseq: NP_001123998
• UniProt ID: Q91YU6