Recombinant Human LZTS2 Protein, MYC/DDK-tagged

• Cat.No.: LZTS2-1265H
• Product Overview: Recombinant human LZTS2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 72.6 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: leucine zipper tumor suppressor 2 [ Homo sapiens ]
• Official Symbol: LZTS2
• Synonyms: LAPSER1
• Gene ID: 84445
• mRNA Refseq: NM_032429.2
• Protein Refseq: NP_115805.1
• MIM: 610454
• UniProt ID: Q9BRK4