Recombinant Mouse Lage3 Protein, Myc/DDK-tagged

• Cat.No.: Lage3-3747M
• Product Overview: Purified recombinant protein of mouse full-length L antigen family, member 3 (Lage3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
• Molecular Mass: 15.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Lage3 L antigen family, member 3 [ Mus musculus (house mouse) ]
• Official Symbol: Lage3
• Synonyms: LAGE3; L antigen family, member 3; L antigen family member 3; ITBA2 protein homolog; Eso3; Itba2; 1110049G11Rik
• Gene ID: 66192
• mRNA Refseq: NM_025410
• Protein Refseq: NP_079686
• UniProt ID: Q9CR70