Recombinant Mouse Kirrel3 Protein, Myc/DDK-tagged

• Cat.No.: Kirrel3-3695M
• Product Overview: Purified recombinant protein of mouse full-length kirre like nephrin family adhesion molecule 3 (Kirrel3), transcript variant C, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells.
• Molecular Mass: 85 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Kirrel3 kirre like nephrin family adhesion molecule 3 [ Mus musculus (house mouse) ]
• Official Symbol: Kirrel3
• Synonyms: KIRREL3; kin of IRRE like 3 (Drosophila); kin of IRRE-like protein 3; X kin of IRRE like 3; membrane protein mKirre; kin of irregular chiasm-like protein 3; SST4; NEPH2; mKIAA1867; 1500010O20Rik; 2900036G11Rik
• Gene ID: 67703
• mRNA Refseq: NM_001190912
• Protein Refseq: NP_001177841
• UniProt ID: Q8BR86