Recombinant Mouse Izumo1 Protein, Myc/DDK-tagged

• Cat.No.: Izumo1-3624M
• Product Overview: Purified recombinant protein of mouse full-length izumo sperm-egg fusion 1 (Izumo1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.
• Molecular Mass: 45.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Izumo1 izumo sperm-egg fusion 1 [ Mus musculus (house mouse) ]
• Official Symbol: Izumo1
• Synonyms: IZUMO1; izumo sperm-egg fusion 1; izumo sperm-egg fusion protein 1; OBF; oocyte binding/fusion factor; sperm-specific protein Izumo; Izumo; 1700058F15Rik
• Gene ID: 73456
• mRNA Refseq: NM_001018013
• Protein Refseq: NP_001018013
• UniProt ID: Q9D9J7