Recombinant Mouse ITGAV&ITGB3 protein, hFc-tagged

• Cat.No.: ITGAV&ITGB3-1563M
• Product Overview: Recombinant Mouse ITGAV&ITGB3 protein(P43406(ITGAV)&&O54890(ITGB3))(Phe31-Val988(ITGAV)& Glu26-Asp717(ITGB3)), fused with C-terminal hFc tag, was expressed in HEK293.

Specification

• Species: Mouse
• Source: C-hFc
• ProteinLength: Phe31-Val988(ITGAV)& Glu26-Asp717(ITGB3)
• Tag: C-hFc
• Form: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Bio-activity: Mouse ITGAV&ITGB3, hFc Tag captured on CM5 Chip via Protein A can bind Human Vitronectin, His Tag with an affinity constant of 3.37 nM as determined in SPR assay (Biacore T200).
• Molecular Mass: The protein has a predicted MW of 131.48 kDa(ITGAV)&101.58 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 110-135 kDa and 50-60 kDa based on Tris-Bis PAGE result.
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC.
• Storage: Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• Reconstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: Itgav integrin alpha V [ Mus musculus ]
• Official Symbol: ITGAV
• Synonyms: ITGAV; integrin alpha V; integrin alpha-V; alphav-integrin; vitronectin receptor subunit alpha; vitronectin receptor alpha polypeptide (VNRA); CD51; 1110004F14Rik; 2610028E01Rik; D430040G12Rik
• Gene ID: 16410
• mRNA Refseq: NM_008402
• Protein Refseq: NP_032428
• Gene Name 2: Itgb3 integrin beta 3 [ Mus musculus ]
• Official Symbol 2: ITGB3
• Synonyms 2: ITGB3; integrin beta 3; integrin beta-3; GPIIIa; platelet gpIIIa; platelet membrane glycoprotein IIIa; CD61; GP3A; INGRB3; MGC159221; MGC159223
• Gene ID 2: 16416
• mRNA Refseq 2: NM_016780
• Protein Refseq 2: NP_058060