Recombinant Mouse Interleukin 31

• Cat.No.: Il31-171M
• Product Overview: Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues. It was expressed inE.Coli.

Specification

• Cat. No.: Il31 -171M
• Description: IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
• Source: E.Coli.
• Purity: > 98% (SDS-PAGE; HPLC).
• Endotoxin Level: < 0.1 ng/μg of IL-31.
• Stabilizer: None.
• Formulation: Lyophilized.
• Biological Activity: Testing in progress.
• Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-31 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
• Tag: Non

Gene Information

• Gene Name: Il31 interleukin 31 [ Mus musculus ]
• Synonyms: interleukin 31; 1700013B14Rik; Il31
• Gene ID: 76399
• mRNA Refseq: NM_029594
• Protein Refseq: NP_083870
• UniProt ID: Q6EAL8
• Chromosome Location: 5 F
• Function: cytokine activity