Recombinant Mouse Interferon Beta 1, Fibroblast

Cat. No. :	Ifnb1-684M
Description :	Ifnb1 is aprotein that in humans is encoded by the Ifnb1 gene.
Source :	E. coli
Species :	Mouse
Form :	Liquid in PBS,carrier free.
Molecular Weight :	19.6 kDa
Concentration :	1 x 106units/ml
Purity :	> 95%
Endotoxin Level :	< 0.1 EU/μg Ifnb1.
Purification :	Combinationof ion exchange, hydrophobic interaction, and size exclusion chromatography.
Specific Activity :	Ifnb1 wastitrated with the use of the cytopathic effect inhibition assay. Units of activitywere measured on mouse L929 cells with encephalomyocarditis virus (EMCV); in thisassay, the EC50 for Ifnb1 is ~ 2.5 U/ml. Theactivity was determined relative to a labstandard of mouse Ifnb1 which was calibrated to the NIH Mouse Ifnb1 standard.
Storage :	Store inworking aliquots at -80°C. Further dilutions should be made in bufferscontainingproteinsuch as 0.1% BSA. Please note that the addition of any carrier proteinintothisproduct may produce unwanted endotoxin. This depends upon the particular applicationemployed. Avoid repeated freeze-thaw cycles.
OfficialSymbol :	Ifnb1
Tag :	Non

Gene Name	Ifnb1 interferon beta 1,fibroblast [ Mus musculus ]
Synonyms	Ifnb1; interferonbeta 1, fibroblast; Ifb; IFNB; IFN-beta; interferon beta; OTTMUSP00000008111
Gene ID	15977
mRNA Refseq	NM_010510
Protein Refseq	NP_034640
Chromosome Location	4 C4; 442.6 cM
Pathway	Chagas disease(American trypanosomiasis); Cytokine-cytokine receptor interaction; Cytokinesand Inflammatory Response (BioCarta); Cytosolic DNA-sensing pathway;Hepatitis C; Herpes simplex infection; Influenza A; Jak-STAT signalingpathway; Measles; Natural killer cell mediated cytotoxicity; Osteoclast;Osteoclast differentiation; RIG-I-like receptor signaling pathway; Senescenceand Autophagy; Toll-like receptor signaling pathway; Tuberculosis; Type IIinterferon signaling (IFNG)
Function	cytokine activity;cytokine receptor binding; transcription corepressor activity