Recombinant Dog IFNB1 Protein, His-tagged

Specification
Gene Information
Related Products
Download

Description :	This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Source :	E. coli
Species :	Dog
Tag :	His
Form :	Freeze-dried powder
Molecular Mass :	Predicted Molecular Mass: 23.8 kDa; Accurate Molecular Mass: 24 kDa
Protein length :	Ala21-Asn186
Purity :	> 90%
Applications :	Positive Control; Immunogen; SDS-PAGE; WB.
Stability :	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage :	Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer :	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution :	Reconstitute in PBS or others.

Gene Name	IFNB1 interferon, beta 1, fibroblast [ Canis lupus familiaris (dog) ]
Official Symbol	IFNB1
Synonyms	IFNB1; interferon, beta 1, fibroblast; interferon beta;
Gene ID	481558
mRNA Refseq	NM_001135787
Protein Refseq	NP_001129259
UniProt ID	B6E116