Recombinant Mouse Ing2 Protein, Myc/DDK-tagged

• Cat.No.: Ing2-3536M
• Product Overview: Purified recombinant protein of mouse full-length inhibitor of growth family, member 2 (Ing2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
• Molecular Mass: 33 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ing2 inhibitor of growth family, member 2 [ Mus musculus (house mouse) ]
• Official Symbol: Ing2
• Synonyms: ING2; inhibitor of growth family, member 2; inhibitor of growth protein 2; inhibitor of growth 1-like protein; Ing1l; Ing2b; P33ING2; 2810011M06Rik
• Gene ID: 69260
• mRNA Refseq: NM_023503
• Protein Refseq: NP_075992
• UniProt ID: Q9ESK4