Recombinant Mouse Impdh2 Protein, Myc/DDK-tagged

• Cat.No.: Impdh2-3532M
• Product Overview: Purified recombinant protein of mouse full-length inosine monophosphate dehydrogenase 2 (Impdh2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
• Molecular Mass: 55.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Impdh2 inosine monophosphate dehydrogenase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Impdh2
• Synonyms: IMPDH2; inosine 5-phosphate dehydrogenase 2; inosine-5-monophosphate dehydrogenase 2; IMPD 2; IMPDH 2; IMPDH-II; IMP dehydrogenase 2; IMP dehydrogenase type II; IMPD
• Gene ID: 23918
• mRNA Refseq: NM_011830
• Protein Refseq: NP_035960
• UniProt ID: P24547