Recombinant Mouse Igf2 protein, His-tagged

• Cat.No.: Igf2-817M
• Product Overview: Recombinant Mouse Igf2 aa. (Ala25~Glu91 (Accession # p09535)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Ala25~Glu91
• Description: This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. It is an imprinted gene that is expressed only from the paternal allele. The encoded protein undergoes proteolytic processing to generate a mature peptide. The transgenic overexpression of this gene in mice results in prenatal overgrowth, polyhydramnios, fetal and neonatal lethality, disproportionate organ overgrowth including tongue enlargement, and skeletal abnormalities. Mice lacking the encoded protein exhibit growth deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
• Form: Freeze-dried powder
• Molecular Mass: 11.2 kDa as determined by SDS-PAGE reducing conditions
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH 7.4.
• Reconstitution: Reconstitute in PBS.

Gene Information

• Gene Name: Igf2 insulin-like growth factor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Igf2
• Synonyms: Igf2; insulin-like growth factor 2; Mpr; M6pr; Peg2; Igf-2; Igf-II; AL033362; insulin-like growth factor II; multiplication-stimulating polypeptide
• Gene ID: 16002
• mRNA Refseq: NM_001122736.2
• Protein Refseq: NP_001116208.1
• UniProt ID: P09535