Recombinant Mouse Ide Protein, His-tagged

• Cat.No.: Ide-1644M
• Product Overview: Recombinant Mouse Ide Protein (Ala753-Pro973) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Ala753-Pro973
• Description: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and peptide binding activity. Involved in insulin catabolic process. Acts upstream of or within amyloid-beta clearance and response to oxidative stress. Located in extracellular exosome. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human IDE (insulin degrading enzyme).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.7 kDa
  Accurate Molecular Mass: 30 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Ide insulin degrading enzyme [ Mus musculus (house mouse) ]
• Official Symbol: Ide
• Synonyms: IDE; insulin degrading enzyme; insulin-degrading enzyme; insulysin; insulinase; insulin protease; AA675336; AI507533; 1300012G03Rik; 4833415K22Rik
• Gene ID: 15925
• mRNA Refseq: NM_031156
• Protein Refseq: NP_112419
• UniProt ID: Q9JHR7