Recombinant Mouse Hsp90b1 Protein, Myc/DDK-tagged

• Cat.No.: Hsp90b1-3449M
• Product Overview: Purified recombinant protein of mouse full-length heat shock protein 90, beta (Grp94), member 1 (Hsp90b1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 92.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hsp90b1 heat shock protein 90, beta (Grp94), member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Hsp90b1
• Synonyms: HSP90B1; heat shock protein 90, beta (Grp94), member 1; endoplasmin; tumor rejection antigen gp96; 94 kDa glucose-regulated protein; tumor rejection antigen (gp96) 1; polymorphic tumor rejection antigen 1; heat shock protein 90 kDa beta member 1; endoplasmic reticulum resident protein 99; transforming growth factor alpha regulated gene 2; TA-3; Tra1; gp96; ERp99; GRP94; Targ2; Tra-1
• Gene ID: 22027
• mRNA Refseq: NM_011631
• Protein Refseq: NP_035761
• UniProt ID: P08113