Recombinant Mouse Hjv Protein, His-tagged

• Cat.No.: Hjv-1624M
• Product Overview: Recombinant Mouse Hjv Protein (Cys34-Asp393) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• ProteinLength: Cys34-Asp393
• Description: Enables BMP binding activity and coreceptor activity. Involved in cellular iron ion homeostasis and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including BMP signaling pathway; iron ion homeostasis; and negative regulation of BMP signaling pathway. Located in cell surface and extracellular space. Is expressed in several structures, including gonad; musculature; submandibular gland; trunk mesenchyme; and yolk sac. Used to study hemochromatosis type 2A. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 2A. Orthologous to human HJV (hemojuvelin BMP co-receptor).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 38.6 kDa
  Accurate Molecular Mass: 69 kDa
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Hjv hemojuvelin BMP co-receptor [ Mus musculus (house mouse) ]
• Official Symbol: Hjv
• Synonyms: Hjv; hemojuvelin BMP co-receptor; DL-M; Hfe2; Rgmc; AI414844; AI789733; hemojuvelin; 2310035L15Rik; 5230400G09Rik; hemojuvelin; RGM domain family member C; hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein homolog; hemojuvelin BMP coreceptor; repulsive guidance molecule C
• Gene ID: 69585
• mRNA Refseq: NM_027126
• Protein Refseq: NP_081402
• UniProt ID: Q7TQ32