Recombinant Mouse Hes6 Protein, Myc/DDK-tagged

• Cat.No.: Hes6-3387M
• Product Overview: Purified recombinant protein of mouse full-length hairy and enhancer of split 6 (Hes6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 24.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hes6 hairy and enhancer of split 6 [ Mus musculus (house mouse) ]
• Official Symbol: Hes6
• Synonyms: HES6; hairy and enhancer of split 6 (Drosophila); transcription cofactor HES-6; bHLHb41; AI326893
• Gene ID: 55927
• mRNA Refseq: NM_019479
• Protein Refseq: NP_062352
• UniProt ID: Q9JHE6