Recombinant Mouse Hax1 Protein, Myc/DDK-tagged

• Cat.No.: Hax1-3362M
• Product Overview: Purified recombinant protein of mouse full-length HCLS1 associated X-1 (cDNA clone MGC:5838 IMAGE:3582652), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 31.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hax1 HCLS1 associated X-1 [ Mus musculus (house mouse) ]
• Official Symbol: Hax1
• Synonyms: Hax1; HCLS1 associated X-1; HAX-; Hs1b; Silg; HAX-1; mHAX-; Hs1bp1; SIG-111; Silg111; mHAX-1s; HSP1BP-1; HCLS1-associated protein X-1; HS1 binding protein; HS1-associated protein X-1; HS1-associating protein X-1
• Gene ID: 23897
• mRNA Refseq: NM_011826
• Protein Refseq: NP_035956
• UniProt ID: O35387