Recombinant Mouse Gpsm1 Protein, Myc/DDK-tagged

• Cat.No.: Gpsm1-3298M
• Product Overview: Purified recombinant protein of mouse full-length G-protein signalling modulator 1 (AGS3-like, C, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
• Molecular Mass: 73 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) [ Mus musculus (house mouse) ]
• Official Symbol: Gpsm1
• Synonyms: Gpsm1; G-protein signalling modulator 1 (AGS3-like, C. elegans); Ag; Ags3; AW107933; 1810037C22Rik; G-protein-signaling modulator 1; activator of G-protein signaling 3
• Gene ID: 67839
• mRNA Refseq: NM_153410
• Protein Refseq: NP_700459
• UniProt ID: Q6IR34