Recombinant Mouse Gpatch3 Protein, Myc/DDK-tagged

• Cat.No.: Gpatch3-3282M
• Product Overview: Purified recombinant protein of mouse full-length G patch domain containing 3 (Gpatch3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6.
• Molecular Mass: 59.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gpatch3 G patch domain containing 3 [ Mus musculus (house mouse) ]
• Official Symbol: Gpatch3
• Synonyms: GPATCH3; G patch domain containing 3; G patch domain-containing protein 3; Gpatc3; D930035B09Rik; MGC106307
• Gene ID: 242691
• mRNA Refseq: NM_172876
• Protein Refseq: NP_766464
• UniProt ID: Q8BIY1