Recombinant Mouse Gopc Protein, Myc/DDK-tagged

• Cat.No.: Gopc-3272M
• Product Overview: Purified recombinant protein of mouse full-length golgi associated PDZ and coiled-coil motif containing (Gopc), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
• Molecular Mass: 49.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gopc golgi associated PDZ and coiled-coil motif containing [ Mus musculus (house mouse) ]
• Official Symbol: Gopc
• Synonyms: GOPC; golgi associated PDZ and coiled-coil motif containing; Golgi-associated PDZ and coiled-coil motif-containing protein; PDZ domain-containing protein PIST; PDZ protein interacting specifically with TC10; CAL; FIG; PIST; GOPC1; AI844555; 2210402P09Rik
• Gene ID: 94221
• mRNA Refseq: NM_053187
• Protein Refseq: NP_444417
• UniProt ID: Q8BH60