Recombinant Mouse Gid8 Protein, Myc/DDK-tagged

• Cat.No.: Gid8-3206M
• Product Overview: Purified recombinant protein of mouse full-length GID complex subunit 8 (Gid8), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 26.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gid8 GID complex subunit 8 [ Mus musculus (house mouse) ]
• Official Symbol: Gid8
• Synonyms: Gid8; GID complex subunit 8; Twa1; AI451474; 2310003C23Rik; 4833420G11Rik; glucose-induced degradation protein 8 homolog; GID complex subunit 8 homolog; protein C20orf11 homolog; two hybrid-associated protein 1 with RanBPM
• Gene ID: 76425
• mRNA Refseq: NM_029607
• Protein Refseq: NP_083883
• UniProt ID: Q9D7M1