Recombinant Mouse Gadd45gip1 Protein, MYC/DDK-tagged

• Cat.No.: Gadd45gip1-199M
• Product Overview: Purified recombinant protein of full-length mouse growth arrest and DNA-damage-inducible, gamma interacting protein 1 (Gadd45gip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.
• Molecular Mass: 26.3 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gadd45gip1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Gadd45gip1
• Synonyms: Gadd45gip1; growth arrest and DNA-damage-inducible, gamma interacting protein 1; Crif1; Plinp1; MRP-L59; AI425883; 2310040G17Rik; growth arrest and DNA damage-inducible proteins-interacting protein 1; 39S ribosomal protein L59, mitochondrial; papillomavirus L2 interacting nuclear protein 1
• Gene ID: 102060
• mRNA Refseq: NM_183358
• Protein Refseq: NP_899202
• UniProt ID: Q9CR59