Recombinant Mouse Fibroblast Growth Factor 21, FLAG-tagged

Cat.No. : Fgf21-414M
Product Overview : Recombinant mouse fibroblast growth factor 21 (FGF-21) (aa 1-210) produced inHEK 293 cellsis fused at the C-terminus to a FLAG-tag.
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Species : Mouse
Source : Human Cells
Tag : Flag
Protein Length : 1-210 a.a.
Description : FGF-21 is preferentially expressed in liver, but an exact knowledge of FGF-21 bioactivity and its mode of action have been lacking to date. FGF-21 is a potent activator of glucose uptake on adipocytes, protects animals from diet-induced obesity when overexpressed in transgenic mice, and lowers blood glucose and triglyceride levels when therapeutically administered to diabetic rodents.
Source/Host : HEK 293 cells.
Purity : ≥90% (SDS-PAGE).
Formulation : Liquid. 0.2μm-filtered solution in PBS.
Concentration : 250μg/ml.
Endotoxin Content : <1EU/µg protein (LAL-test).
Long Term Storage : -20°C.
Use/Stability : Working aliquots are stable for up to 3 months when stored at -20°C.
Handling : Avoid freeze/thaw cycles.After opening, prepare aliquots and store at -20°C.
Gene Name Fgf21 fibroblast growth factor 21 [ Mus musculus ]
Synonyms Fgf21; fibroblast growth factor 21;FGF-21
Gene ID 56636
mRNA Refseq NM_020013
Protein Refseq NP_064397
UniProt ID Q9JJN1
Chromosome Location 7 B2
Pathway MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton
Function growth factor activity

Not For Human Consumption!

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