Recombinant Mouse Fgf21, Fc-tagged

• Cat.No.: Fgf21-258M
• Product Overview: Mouse FGF-21 (aa 1-210) is fused at the C-terminus to the Fc portion of human IgG.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Fc
• Protein Length: 1-210 a.a.
• Description: FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Molecular Mass: ~50kDa (SDS-PAGE)
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Fgf21 fibroblast growth factor 21 [ Mus musculus ]
• Official Symbol: Fgf21
• Synonyms: FGF21; fibroblast growth factor 21; FGF-21
• Gene ID: 56636
• mRNA Refseq: NM_020013
• Protein Refseq: NP_064397
• Pathway: ESC Pluripotency Pathways, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Melanoma, organism-specific biosystem; Melanoma, conserved biosystem; Pathways in cancer, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem
• Function: fibroblast growth factor receptor binding; growth factor activity