Recombinant Mouse Fbn1 protein, His-tagged

Cat.No. : Fbn1-2625M
Product Overview : Recombinant Mouse Fbn1 aa. (Leu455~Asp632) fused with N-terminal His tag was produced in E. coli cells.
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Species : Mouse
Source : E.coli
Tag : His
Protein Length : Leu455~Asp632
Description : This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Homozygous knockout mice for this gene exhibit impaired aortic development and early postnatal death, which was attributed to a deficiency in the fibrillin-1 protein. Mice with a hypomorphic allele of this gene exhibit impaired glucose homeostasis, likely due to a reduction in serum asprosin levels.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 21.2kDa
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 5.6.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
Gene Name Fbn1 fibrillin 1 [ Mus musculus (house mouse) ]
Official Symbol Fbn1
Synonyms Fbn1; fibrillin 1; Tsk; Fib-1; AI536462; B430209H23; fibrillin-1; tight skin
Gene ID 14118
mRNA Refseq XM_006498747.1
Protein Refseq XP_006498810.1
UniProt ID Q61554

Not For Human Consumption!

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