Recombinant Mouse Fbn1 Protein, His-tagged

Cat.No. : Fbn1-1465M
Product Overview : Recombinant Mouse Fbn1 Protein (Leu457-Asp634) with N-His tag was expressed in E. coli.
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Species : Mouse
Source : E.coli
Tag : His
Protein Length : Leu457-Asp634
Description : This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Homozygous knockout mice for this gene exhibit impaired aortic development and early postnatal death, which was attributed to a deficiency in the fibrillin-1 protein. Mice with a hypomorphic allele of this gene exhibit impaired glucose homeostasis, likely due to a reduction in serum asprosin levels.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 13.4 kDa
Accurate Molecular Mass: 21 kDa
Purity : > 97%
Applications : Cell culture; Activity Assays.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name Fbn1 fibrillin 1 [ Mus musculus (house mouse) ]
Official Symbol Fbn1
Synonyms FBN1; fibrillin 1; fibrillin-1; tight skin; Tsk; Fib-1; AI536462; B430209H23;
Gene ID 14118
mRNA Refseq NM_007993
Protein Refseq NP_032019
UniProt ID P35555

Not For Human Consumption!

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