Recombinant Mouse Fat Mass And Obesity Associated, His-tagged

• Cat.No.: Fto-2127M
• Product Overview: Recombinant Mouse Fat Mass And Obesity Associated was expressed inE. coli. The mature peptide of mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 2-502 a.a.
• Description: TheFTO (fat mass and obesity-associated) gene is well conserved and found in a single copy in vertebrate species. It is suggested that the FTO protein plays a role in fat cell lipolysis, which may be important in explaining why theFTO gene (and FTO gene variants) is implicated in body weight regulation.
• Purity: ≥95% (SDS-PAGE). Purified by Ni-NTA column and FPLC (Mono Q column).
• Formulation: Liquid. 0.2μm-filtered solution in 50mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
• Concentration: ~0.5mg/ml.
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.

Gene Information

• Gene Name: Fto fat mass and obesity associated [ Mus musculus ]
• Synonyms: Fto; fat mass and obesity associated; AW743446; mKIAA1752; protein fto; protein fatso; OTTMUSP00000031320; fat mass and obesity-associated protein
• Gene ID: 26383
• mRNA Refseq: NM_011936
• Protein Refseq: NP_036066
• UniProt ID: Q8BGW1
• Chromosome Location: 8 C5; 8 41.9 cM
• Function: DNA demethylase activity; molecular_function