Recombinant Mouse F2 Protein, MYC/DDK-tagged

• Cat.No.: F2-995M
• Product Overview: Purified recombinant protein of full-length mouse coagulation factor II (F2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: This gene encodes a vitamin K-dependent glycoprotein coagulation factor that plays an important role in the process of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that undergoes enzymatic cleavage by the coagulation factor Xa to form an active serine protease that converts soluble fibrinogen to insoluble fibrin clot. Most of the mice lacking the encoded protein die at an embryonic stage due to defects in yolk sac vasculature, while the rare nenonates succumb to hemorrhage on the first postnatal day.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 70.7 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: F2 coagulation factor II [ Mus musculus (house mouse) ]
• Official Symbol: F2
• Synonyms: F2; coagulation factor II; Cf2; FII; Cf-2; prothrombin; thrombin; EC 3.4.21.5
• Gene ID: 14061
• mRNA Refseq: NM_010168
• Protein Refseq: NP_034298
• UniProt ID: P19221