Recombinant Mouse Epstein-Barr Virus Induced Gene 3

• Cat.No.: Ebi3-1317M
• Product Overview: Recombinant Mouse EBI produced inE.coliis a non-glycosylated polypeptide chain consisting of 207 amino acids with a molecular weight of 23 kDa.

Specification

• Cat. No.: Ebi3-1317M
• Description: Epstein-Barr Virus Induced Gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family and related to the p40 subunit of IL-12. It was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.
• Source: E.coli.
• AA Sequence: MALVALSQPR VQCHASRYPV AVDCSWTPLQ APNSTRSTSF IATYRLGVAT QQQSQPCLQR SPQASRCTIP DVHLFSTVPY MLNVTAVHPG GASSSLLAFV AERIIKPDPP EGVRLRTAGQ RLQVLWHPPA SWPFPDIFSL KYRLRYRRRG ASHFRQVGPI EATTFTLRNS KPHAKYCIQV SAQDLTDYGK PSDWSLPGQV ESAPHKP
• Formulation: Lyophilized from 10 mM NaCitrate, pH 3.0.
• Purity: Greater than 90% as determined by: (1) Reducing and non-reducing SDS-PAGE. (2) Analytical HPLC.
• Biological Activity: Assay data for mouse recombinant EBI-3 is based upon qualitative binding to anti-EBI-3 antibody.
• Endotoxin: Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
• Protein Content: Determined by: (1) UV spectroscopy at 280 nm. (2) Quantitation on SDS-PAGE against a known standard.
• Reconstitution: It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 - 0.5 mg /ml, which can be further diluted into other aqueous solutions.
• Stability: Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
• Tag: Non

Gene Information

• Gene Name: Ebi3 Epstein-Barr virus induced gene 3 [ Mus musculus ]
• Synonyms: Ebi3; Epstein-Barr virus induced gene 3; EBI-3; IL-27; Epstein-Barr virus induced 3
• Gene ID: 50498
• mRNA Refseq: NM_015766
• Protein Refseq: NP_056581
• UniProt ID: O35228
• Chromosome Location: 17 33.0 cM
• Function: cytokine activity; cytokine receptor activity; interleukin-27 receptor binding; protein binding