Recombinant Human EBI3, Fc-tagged

• Cat.No.: EBI3-27965TH
• Product Overview: Human Epstein-Barr Virus-induced Gene 3 (aa 1-229) is fused at the C-terminus to the Fc portion of human IgG1.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 1-229 a.a.
• Description: This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Molecular Mass: ~60kDa (SDS-PAGE)
• Endotoxin: <0.1eu g="" purified="" protein="" (lal="" test;="" lonza).="">
• Purity: ≥95% (SDS-PAGE)
• Storage: Short Term Storage: +4°C, Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 0.3 mg/ml

Gene Information

• Gene Name: EBI3 Epstein-Barr virus induced 3 [ Homo sapiens ]
• Official Symbol: EBI3
• Synonyms: EBI3; Epstein-Barr virus induced 3; interleukin-27 subunit beta; IL27 subunit; IL35 subunit; cytokine receptor; IL-27 subunit beta; EBV-induced gene 3 protein; Epstein-Barr virus induced gene 3; epstein-Barr virus-induced gene 3 protein; IL27B; IL-27B
• Gene ID: 10148
• mRNA Refseq: NM_005755
• Protein Refseq: NP_005746
• MIM: 605816
• UniProt ID: Q14213
• Chromosome Location: 19p13
• Pathway: IL27-mediated signaling events, organism-specific biosystem
• Function: cytokine activity; cytokine receptor activity; interleukin-27 receptor binding