Recombinant Mouse Elk4 Protein, Myc/DDK-tagged

• Cat.No.: Elk4-2799M
• Product Overview: Purified recombinant protein of mouse full-length ELK4, member of ETS oncogene family (Elk4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.
• Molecular Mass: 46.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Elk4 ELK4, member of ETS oncogene family [ Mus musculus (house mouse) ]
• Official Symbol: Elk4
• Synonyms: ELK4; ELK4, member of ETS oncogene family; ETS domain-containing protein Elk-4; SRF accessory protein 1; serum response factor accessory protein 1; Sap1; SAP-1; BB162516; 2310011G17Rik; A130026I01Rik
• Gene ID: 13714
• mRNA Refseq: NM_007923
• Protein Refseq: NP_031949
• UniProt ID: P41158