Recombinant Mouse Dok1 Protein, Myc/DDK-tagged

• Cat.No.: Dok1-2629M
• Product Overview: Purified recombinant protein of mouse full-length docking protein 1 (Dok1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
• Molecular Mass: 52.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dok1 docking protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Dok1
• Synonyms: DOK1; docking protein 1; p62(dok); downstream of tyrosine kinase 1; p62DOK; AW557123
• Gene ID: 13448
• mRNA Refseq: NM_010070
• Protein Refseq: NP_034200
• UniProt ID: P97465