Recombinant Mouse Dll3 protein, Fc-tagged

• Cat.No.: Dll3-32M
• Product Overview: Recombinant Mouse Dll3(aa 25-490) fused with the Fc portion of human IgG1 at C-terminal was expressed in HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Fc
• Protein Length: 25-490 a.a.
• Description: DLL3 (Delta-like protein 3; Delta3) inhibits primary neurogenesis. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 binds and activates Notch-1. Defects in DLL3 are the cause of spondylocostal dysostosis type 1 (SCDO1).
• Form: Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
• Molecular Mass: ~90kDa (SDS-PAGE)
• Endotoxin: <0.1EU/μg purified protein (LAL test; Lonza).
• Purity: ≥90% (SDS-PAGE)
• Storage: Short Term Storage: +4 centigrade;
  Long Term Storage: -20 centigrade;
  Handling Advice: After opening, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Dll3 delta-like 3 (Drosophila) [ Mus musculus ]
• Official Symbol: Dll3
• Synonyms: DLL3; delta-like 3 (Drosophila); delta-like protein 3; delta3; M-Delta-3; drosophila Delta homolog 3; pu; pudgy
• Gene ID: 13389
• mRNA Refseq: NM_007866
• Protein Refseq: NP_031892
• UniProt ID: O88516
• Chromosome Location: 7 A3; 7 16.67 cM
• Pathway: Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem
• Function: Notch binding; Notch binding; protein binding