Recombinant Mouse Ddx6 Protein, Myc/DDK-tagged

• Cat.No.: Ddx6-2515M
• Product Overview: Purified recombinant protein of mouse full-length DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 54.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [ Mus musculus (house mouse) ]
• Official Symbol: Ddx6
• Synonyms: DDX6; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; probable ATP-dependent RNA helicase DDX6; DEAD box protein 6; oncogene RCK homolog; ATP-dependent RNA helicase p54; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 6; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 6; p54; rck; HLR2; mRCK/P54; 1110001P04Rik; E230023J21Rik
• Gene ID: 13209
• mRNA Refseq: NM_007841
• Protein Refseq: NP_031867
• UniProt ID: P54823