Recombinant Mouse Dcc Protein, Myc/DDK-tagged

• Cat.No.: Dcc-2470M
• Product Overview: Purified recombinant protein of mouse full-length deleted in colorectal carcinoma (Dcc), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
• Molecular Mass: 158.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dcc deleted in colorectal carcinoma [ Mus musculus (house mouse) ]
• Official Symbol: Dcc
• Synonyms: DCC; deleted in colorectal carcinoma; netrin receptor DCC; tumor suppressor protein DCC; Igdcc1; C030036D22Rik
• Gene ID: 13176
• mRNA Refseq: NM_007831
• Protein Refseq: NP_031857
• UniProt ID: P70211