Recombinant Mouse Cyth2 Protein, Myc/DDK-tagged

• Cat.No.: Cyth2-2429M
• Product Overview: Purified recombinant protein of mouse full-length cytohesin 2 (Cyth2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Involved in neurite growth.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 46.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cyth2 cytohesin 2 [ Mus musculus (house mouse) ]
• Official Symbol: Cyth2
• Synonyms: CYTH2; cytohesin 2; cytohesin-2; mSec7-2; SEC7 homolog B; pleckstrin homology, Sec7 and coiled-coil domains 2; PH, SEC7 and coiled-coil domain-containing protein 2; ARNO; CLM2; Pscd2
• Gene ID: 19158
• mRNA Refseq: NM_011181
• Protein Refseq: NP_035311
• UniProt ID: P63034