Recombinant Mouse Corin Protein, Myc/DDK-tagged

• Cat.No.: Corin-2271M
• Product Overview: Purified recombinant protein of mouse full-length corin, serine peptidase (Corin), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
• Molecular Mass: 123.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Corin corin, serine peptidase [ Mus musculus (house mouse) ]
• Official Symbol: Corin
• Synonyms: CORIN; corin; atrial natriuretic peptide-converting enzyme; pro-ANP-converting enzyme; low density lipoprotein-related protein 4; low density lipoprotein receptor-related protein 4; Lrp4; AV273130; MGC118735
• Gene ID: 53419
• mRNA Refseq: NM_016869
• Protein Refseq: NP_058565
• UniProt ID: Q9Z319