Recombinant Mouse Cenpa Protein, MYC/DDK-tagged

• Cat.No.: Cenpa-877M
• Product Overview: Purified recombinant protein of full-length mouse centromere protein A (Cenpa), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 15.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cenpa centromere protein A [ Mus musculus (house mouse) ]
• Official Symbol: Cenpa
• Synonyms: Cenpa; centromere protein A; Cenp-A; histone H3-like centromeric protein A; centromere autoantigen A; centrosomin A
• Gene ID: 12615
• mRNA Refseq: NM_007681
• Protein Refseq: NP_031707
• UniProt ID: O35216