Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged
Cat.No. : | Cdkn2c-871M |
Product Overview : | Purified recombinant protein of full-length mouse cyclin dependent kinase inhibitor 2C (Cdkn2c), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
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Species : | Mouse |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase (cdk) inhibitors, and contains five ankyrin repeats. This protein interacts with both Cdk4 and Cdk6 to inhibit their kinase activities, and prevent their interactions with D-type cyclins, thereby negatively regulating cell division. This gene is differentially expressed in a variety of tissues, and is cell cycle regulated. Deletion of this gene can lead to tumor growth. Maximal expression is observed at the G2/M phase. Alternative splicing and promoter usage results in multiple transript variants. |
Molecular Mass : | 18.1 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name | Cdkn2c cyclin dependent kinase inhibitor 2C [ Mus musculus (house mouse) ] |
Official Symbol | Cdkn2c |
Synonyms | Cdkn2c; cyclin dependent kinase inhibitor 2C; p18; INK4c; C77269; p18-INK6; p18INK4c; p18-INK4c; cyclin-dependent kinase 4 inhibitor C; cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
Gene ID | 12580 |
mRNA Refseq | NM_007671 |
Protein Refseq | NP_031697 |
UniProt ID | Q60772 |
◆ Recombinant Proteins | ||
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CDKN2C-622R | Recombinant Rhesus Macaque CDKN2C Protein, His (Fc)-Avi-tagged | +Inquiry |
CDKN2C-4708H | Recombinant Human CDKN2C Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
CDKN2C-796R | Recombinant Rhesus monkey CDKN2C Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CDKN2C-7612HCL | Recombinant Human CDKN2C 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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