Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged

• Cat.No.: Cdkn2c-871M
• Product Overview: Purified recombinant protein of full-length mouse cyclin dependent kinase inhibitor 2C (Cdkn2c), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase (cdk) inhibitors, and contains five ankyrin repeats. This protein interacts with both Cdk4 and Cdk6 to inhibit their kinase activities, and prevent their interactions with D-type cyclins, thereby negatively regulating cell division. This gene is differentially expressed in a variety of tissues, and is cell cycle regulated. Deletion of this gene can lead to tumor growth. Maximal expression is observed at the G2/M phase. Alternative splicing and promoter usage results in multiple transript variants.
• Molecular Mass: 18.1 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cdkn2c cyclin dependent kinase inhibitor 2C [ Mus musculus (house mouse) ]
• Official Symbol: Cdkn2c
• Synonyms: Cdkn2c; cyclin dependent kinase inhibitor 2C; p18; INK4c; C77269; p18-INK6; p18INK4c; p18-INK4c; cyclin-dependent kinase 4 inhibitor C; cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
• Gene ID: 12580
• mRNA Refseq: NM_007671
• Protein Refseq: NP_031697
• UniProt ID: Q60772