Recombinant Mouse Cd22 Protein, MYC/DDK-tagged

• Cat.No.: Cd22-831M
• Product Overview: Purified recombinant protein of full-length mouse CD22 antigen (Cd22), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
• Molecular Mass: 97.6 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cd22 CD22 antigen [ Mus musculus (house mouse) ]
• Official Symbol: Cd22
• Synonyms: Cd22; CD22 antigen; Lyb8; Lyb-8; A530093D23; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; T-cell surface antigen Leu-14; sialic acid-binding Ig-like lectin 2; siglec-2
• Gene ID: 12483
• mRNA Refseq: NM_001043317
• Protein Refseq: NP_001036782
• UniProt ID: P35329