Active Recombinant Human CD22 Protein, Fc-tagged, Atto 488 conjugated

• Cat.No.: CD22-23H
• Product Overview: Recombinant human Atto 488 conjugated Siglec-2/CD22 (Asp20-Arg687) protein with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in mouse myeloma cell line.

Specification

• Species: Human
• Source: NS0
• Tag: Fc
• Description: Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
• Form: Disulfide-linked homodimer
  Labeled with Atto 488 via amines
  Excitation Wavelength: 501 nm
  Emission Wavelengh: 523 nm
• Bio-activity: Measured by flow cytometry for its ability to bind anti-Human Siglec-2/CD22 Monoclonal Antibody conjugated fluorescent beads.
• Molecular Mass: 101.9 kDa
• N-terminal Sequence Analysis: Asp20
• Endotoxin: <1.0 EU/μg of the protein by the LAL method.
• Purity: >80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after opening.
  3 months, -20 to -70 centigrade under sterile conditions after opening.
• Storage Buffer: Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Shipping: The product is shipped with dry ice or equivalent.

Gene Information

• Gene Name: CD22 CD22 molecule [ Homo sapiens (human) ]
• Official Symbol: CD22
• Synonyms: CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; sialic acid-binding Ig-like lectin 2
• Gene ID: 933
• mRNA Refseq: NM_001771
• Protein Refseq: NP_001762
• MIM: 107266
• UniProt ID: P20273