Recombinant Mouse Camkk2 Protein, Myc/DDK-tagged

• Cat.No.: Camkk2-1947M
• Product Overview: Purified recombinant protein of mouse full-length calcium/calmodulin-dependent protein kinase kinase 2, beta (Camkk2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK4 and CAMK1D. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca2+ signals. May play a role in neurite growth. Isoform 2 may promote neurite elongation, while isoform 1 may promoter neurite branching. May be involved in hippocampal activation of CREB1.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 59.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta [ Mus musculus (house mouse) ]
• Official Symbol: Camkk2
• Synonyms: CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2, beta; calcium/calmodulin-dependent protein kinase kinase 2; caMKK 2; caM-KK 2; caMKK beta; caM-KK beta; caM-kinase kinase 2; caM-kinase kinase beta; calcium/calmodulin-dependent protein kinase kinase beta; AW061083; mKIAA0787; 6330570N16Rik
• Gene ID: 207565
• mRNA Refseq: NM_145358
• Protein Refseq: NP_663333
• UniProt ID: Q8C078